About me

I am an EMBO long-term Postdoctoral fellow at the Garvan Institute of Medical Research (in Sydney, Australia) in Joseph Powell’s and Daniel MacArthur’s labs. Previously, I completed postdoctoral training at the Wellcome Trust Sanger Institute in Nicole Soranzo’s group, and I obtained my PhD in Statistical Genetics at the University of Cambridge and the European Bioinformatics Institute, under the joint supervision of Oliver Stegle and John Marioni. Before that, I obtained my Master’s in Computer Science, track Bioinformatics from the Delft University of Technology, The Netherlands, and Bachelor’s degree in Mathematical Engineering from the Politecnico di Milano, Italy.

My PhD and postdoc work is concerned with the development of integrative statistical models to link DNA variants to single cell expression profiles, to uncover molecular mechanisms that might help unravelling the genotype-phenotype map. As part of this effort I have contributed to the analysis of datasets from the HipSci (Human Induced Pluripotent Stem Cells Initiative) project, the HCA (Human Cell Atlas) and the sc-eQTL Gen (single-cell eQTL Gen) consortia. I am currently contributing to the analysis of data from phase 1 of the TenK10K project (stemming from the OneK1K project), where I study the effects of different classes of genetic variation (including rare and structural variants) on blood single-cell expression profiles from 2,000+ Australian individuals.