Pick a perturbation above to see its top affected genes.
Surprise (z-score): how unusual the change is compared with the gene’s natural cell-to-cell variation in control cells.
Fold change (log2 after ÷ before): how much the level moved relative to where it started. Near-silent genes switching on score highest.
Absolute change (after − before, per cell): how much the level moved in absolute terms. Abundant genes, such as ribosomal proteins, score highest.
Fold and absolute changes are approximated from the published per-gene means.
Solid bars are significant at FDR 5% against a null built from the non-targeting control cells (scaled by cell number); faded bars are not. Hover a bar for before → after. How these numbers are calculated.